A stereoselective synthesis of a 2-functionalized-methyl-1β-methylcarbapenem key intermediate via decarboxylation

被引：8

作者：

Choi, WB ^{[1
]}

Lee, J ^{[1
]}

Lynch, JE ^{[1
]}

Volante, RP ^{[1
]}

Reider, PJ ^{[1
]}

Reamer, RA ^{[1
]}

机构：

[1] Merck Res Labs, Rahway, NJ 07065 USA

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 17期

关键词：

D O I：

10.1039/a804125c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of a key intermediate 2a for the synthesis of 2-functionalized methyl-1 beta-methylcarbapenem antibiotics 1 has been realized via a stereoselective decarboxylation reaction.

引用

页码：1817 / 1818

页数：2

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