SNPTools: a software tool for visualization and analysis of microarray data

被引：2
|
作者：
Sorensen, Frank J.
Andersen, Claus L.
Wiuf, Carsten
机构：
[1] Aarhus Univ Hosp, Mol Diagnost Lab, DK-8200 Aarhus, Denmark
[2] Aarhus Univ, Bioinformat Res Ctr, Aarhus, Denmark
来源：
BIOINFORMATICS | 2007年 / 23卷 / 12期
关键词：
D O I：
10.1093/bioinformatics/btm122
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs.
引用
收藏
页码：1550 / 1552
页数：3
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