Treatment of Skin Cancers in Epidermolysis Bullosa

被引:18
|
作者
Venugopal, Supriya S. [1 ]
Murrell, Dedee F. [1 ]
机构
[1] Univ New S Wales, St George Hosp, Dept Dermatol, Sydney, NSW 2217, Australia
关键词
Epidermolysis bullosa; Biopsy; Diagnosis; SQUAMOUS-CELL CARCINOMA; MARJOLINS-ULCER; GROWTH-FACTOR; SINGLE-AGENT; NODE BIOPSY; HEAD; CETUXIMAB; BURN; EXPRESSION; MANAGEMENT;
D O I
10.1016/j.det.2010.01.009
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Squamous cell carcinomas (SCCs) are highly aggressive in patients with epidermolysis bullosa (EB). Non ultraviolet-related SCCs are the leading cause of death in patients with recessive dystrophic EB, particularly recessive dystrophic EB-generalized severe subtype (RDEB-GS). The mechanism of SCC development in patients with RDEB continues to be investigated and several theories have been reported in the literature.
引用
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页码:283 / +
页数:7
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