Kaposi's sarcoma-associated herpes virus (KSHV), the causative agent of several neoplasms, has recently been shown to encode 12 microRNAs. mir-155 is a host-encoded microRNA associated with lymphomagenesis. Two new papers provide strong evidence that a KSHV-encoded microRNA and mir-155 share a common set of mRNA targets and binding sites, implying a possible link between viral- and non-viral-mediated tumorigenesis.
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Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Cancer Epidemiology Research Group, National Health Laboratory Services, JohannesburgDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Malope-Kgokong B.I.
MacPhail P.
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Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, JohannesburgDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
MacPhail P.
Mbisa G.
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Viral Oncology Section, AIDS, NCI-Frederick, Frederick, MDDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Mbisa G.
Ratshikhopha E.
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Cancer Epidemiology Research Group, National Health Laboratory Services, JohannesburgDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Ratshikhopha E.
Maskew M.
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Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, JohannesburgDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Maskew M.
Stein L.
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Cancer Epidemiology Research Group, National Health Laboratory Services, JohannesburgDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Stein L.
Sitas F.
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Cancer Research Division, Cancer Council, NSWDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
Sitas F.
Whitby D.
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Viral Oncology Section, AIDS, NCI-Frederick, Frederick, MDDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg