Kaposi's sarcoma herpes virus taps into a host microRNA regulatory network

被引：40
|
作者：
McClure, Lydia V. [1 ]
Sullivan, Christopher S. [1 ]
机构：
[1] Univ Texas Austin, Austin, TX 78712 USA
来源：
CELL HOST & MICROBE | 2008年 / 3卷 / 01期
关键词：
D O I：
10.1016/j.chom.2007.12.002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Kaposi's sarcoma-associated herpes virus (KSHV), the causative agent of several neoplasms, has recently been shown to encode 12 microRNAs. mir-155 is a host-encoded microRNA associated with lymphomagenesis. Two new papers provide strong evidence that a KSHV-encoded microRNA and mir-155 share a common set of mRNA targets and binding sites, implying a possible link between viral- and non-viral-mediated tumorigenesis.
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页码：1 / 3
页数：3
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