Development of two pentaplex systems with X-chromosomal STR loci and their allele frequencies in a northeast German population

被引：35
|
作者：
Poetsch, M [1 ]
Petersmann, H [1 ]
Repenning, A [1 ]
Lignitz, E [1 ]
机构：
[1] Ernst Moritz Arndt Univ Greifswald, Inst Forens Med, D-17489 Greifswald, Germany
来源：
FORENSIC SCIENCE INTERNATIONAL | 2005年 / 155卷 / 01期
关键词：
X chromosome; STR; multiplex; population data;
D O I：
10.1016/j.forsciint.2004.11.016
中图分类号：
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号：
0301 ; 10 ;
摘要：
In this study we present two new pentaplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-penta-1 comprises DXS9898, DXS6807, HPRTB, DXS101, and androgen receptor (ARA); X-penta-2 consists of DXS7133, DXS 100 11, DXS7424, DXS8377, and DXS8378. In addition, allele frequencies for these loci in a northeast German population comprising 100 females and 105 males were shown. The applicability and usefulness of our two PCR pentaplex approaches in paternity deficiency cases is demonstrated by a combined power of discrimination (PDc) for both females and males with PDc > 0.999999. (c) 2004 Published by Elsevier Ireland Ltd.
引用
收藏
页码：71 / 76
页数：6
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