Development of two pentaplex systems with X-chromosomal STR loci and their allele frequencies in a northeast German population

被引：35

作者：

Poetsch, M ^{[1
]}

Petersmann, H ^{[1
]}

Repenning, A ^{[1
]}

Lignitz, E ^{[1
]}

机构：

[1] Ernst Moritz Arndt Univ Greifswald, Inst Forens Med, D-17489 Greifswald, Germany

来源：

FORENSIC SCIENCE INTERNATIONAL | 2005年 / 155卷 / 01期

关键词：

X chromosome; STR; multiplex; population data;

D O I：

10.1016/j.forsciint.2004.11.016

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

In this study we present two new pentaplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-penta-1 comprises DXS9898, DXS6807, HPRTB, DXS101, and androgen receptor (ARA); X-penta-2 consists of DXS7133, DXS 100 11, DXS7424, DXS8377, and DXS8378. In addition, allele frequencies for these loci in a northeast German population comprising 100 females and 105 males were shown. The applicability and usefulness of our two PCR pentaplex approaches in paternity deficiency cases is demonstrated by a combined power of discrimination (PDc) for both females and males with PDc > 0.999999. (c) 2004 Published by Elsevier Ireland Ltd.

引用

页码：71 / 76

页数：6

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