HIV-1 Latency by Transition

被引:1
|
作者
Julg, Boris [1 ,2 ]
Barouch, Dan H. [1 ,2 ]
机构
[1] Beth Israel Deaconess Med Ctr, Ctr Virol & Vaccine Res, Boston, MA 02115 USA
[2] Ragon Inst Massachusetts Gen Hosp Massachusetts I, Cambridge, MA 02139 USA
关键词
CD4(+) T-CELLS; RHESUS-MONKEYS; RESERVOIR; INFECTION;
D O I
10.1016/j.immuni.2017.09.019
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The latent HIV-1 reservoir represents the major barrier for the development of an HIV-1 cure. In this issue of Immunity, Shan et al. (2017) highlight that effector-to-memory transitioning (EMT) CD4(+) T cells are particularly permissive for the establishment of latent HIV-1 infection.
引用
收藏
页码:611 / 612
页数:2
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