Molecular markers in the diagnostics and therapy of urothelial cancer

被引:4
|
作者
Protzel, C. [1 ]
Hakenberg, O. W. [1 ]
机构
[1] Urol Univ Klin Rostock, Klin & Poliklin Urol, D-18057 Rostock, Germany
来源
UROLOGE | 2010年 / 49卷 / 11期
关键词
Urinary bladder cancer; Disease progression; Urine; Genetics; Tumor markers; biological; POLYMERASE-CHAIN-REACTION; TRANSITIONAL-CELL CARCINOMA; CIRCULATING TUMOR-CELLS; GROWTH-FACTOR RECEPTOR; BLADDER-CANCER; PERIPHERAL-BLOOD; PROGNOSTIC-SIGNIFICANCE; SURVIVIN EXPRESSION; FGFR3; MUTATIONS; IN-SITU;
D O I
10.1007/s00120-010-2431-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Many clinical decisions in the management of bladder cancer would benefit from better and reliable knowledge of individual prognosis. Marker for urothelial cancer can principally be measured in blood, urine and transurethrally resected tissue. In recent years new markers have been identified by new technologies and this opens exiting avenues. Since no single marker gives a clear Yes-or-no prognostic answer but always only a measure of probability, the use of marker systems has so far not gained widespread clinical applications. This will likely change in future.
引用
收藏
页码:1415 / 1423
页数:9
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