Molecular markers in the diagnostics and therapy of urothelial cancer

被引:4
|
作者
Protzel, C. [1 ]
Hakenberg, O. W. [1 ]
机构
[1] Urol Univ Klin Rostock, Klin & Poliklin Urol, D-18057 Rostock, Germany
来源
UROLOGE | 2010年 / 49卷 / 11期
关键词
Urinary bladder cancer; Disease progression; Urine; Genetics; Tumor markers; biological; POLYMERASE-CHAIN-REACTION; TRANSITIONAL-CELL CARCINOMA; CIRCULATING TUMOR-CELLS; GROWTH-FACTOR RECEPTOR; BLADDER-CANCER; PERIPHERAL-BLOOD; PROGNOSTIC-SIGNIFICANCE; SURVIVIN EXPRESSION; FGFR3; MUTATIONS; IN-SITU;
D O I
10.1007/s00120-010-2431-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Many clinical decisions in the management of bladder cancer would benefit from better and reliable knowledge of individual prognosis. Marker for urothelial cancer can principally be measured in blood, urine and transurethrally resected tissue. In recent years new markers have been identified by new technologies and this opens exiting avenues. Since no single marker gives a clear Yes-or-no prognostic answer but always only a measure of probability, the use of marker systems has so far not gained widespread clinical applications. This will likely change in future.
引用
收藏
页码:1415 / 1423
页数:9
相关论文
共 50 条
  • [1] Molecular markers of urothelial cancer and their use in the monitoring of superficial urothelial cancer
    Black, Peter C.
    Brown, Gordon A.
    Dinney, Colin P.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (35) : 5528 - 5535
  • [2] Molekulare Marker in Diagnostik und Therapie des UrothelkarzinomsMolecular markers in the diagnostics and therapy of urothelial cancer
    C. Protzel
    O.W. Hakenberg
    [J]. Der Urologe, 2010, 49 : 1415 - 1424
  • [3] Molecular Markers in Thyroid Cancer Diagnostics
    Kato, Meredith A.
    Fahey, Thomas J., III
    [J]. SURGICAL CLINICS OF NORTH AMERICA, 2009, 89 (05) : 1139 - +
  • [4] Molecular markers of systemic therapy response in urothelial carcinoma
    Claps, Francesco
    Mir, Maria Carmen
    Zargar, Homayoun
    [J]. ASIAN JOURNAL OF UROLOGY, 2021, 8 (04) : 376 - 390
  • [5] Molecular markers of systemic therapy response in urothelial carcinoma
    Francesco Claps
    Maria Carmen Mir
    Homayoun Zargar
    [J]. Asian Journal of Urology., 2021, (04) - 390
  • [6] Molecular markers of carcinogenesis in the diagnostics of cervical cancer
    Bedkowska, Grazyna Ewa
    Lawicki, Slawomir
    Szmitkowski, Maciej
    [J]. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, 2009, 63 : 99 - 105
  • [7] Novel Molecular Targets for the Therapy of Urothelial Cancer
    Jana, Bagi R. P.
    Zhou, Yan
    [J]. ANTICANCER RESEARCH, 2015, 35 (09) : 4557 - 4567
  • [8] The Role of Molecular Markers in Thyroid Cancer Diagnostics and Treatment
    Sada, Alaa
    Yip, Linwah
    [J]. SURGICAL CLINICS OF NORTH AMERICA, 2024, 104 (04) : 741 - 749
  • [9] Molecular markers development for early diagnostics of human colon cancer
    Kabdullina, A. A.
    Berillo, O. A.
    Khailenko, V. A.
    Achsheulov, A. S.
    Tauasarova, M. K.
    Atambayeva, S. A.
    [J]. NEW BIOTECHNOLOGY, 2010, 27 : S56 - S56
  • [10] Molecular diagnostics in bladder cancer-predictive and prognostic markers
    Rueschoff, Jan H.
    Moch, Holger
    [J]. ONKOLOGIE, 2022, 28 (09): : 742 - 752