Lanostane and Hopane Triterpenes from the Entomopathogenic Fungus Hypocrella sp BCC 14524

被引:16
|
作者
Isaka, Masahiko [1 ]
Chinthanom, Panida [1 ]
Sappan, Malipan [1 ]
Chanthaket, Rungtiwa [1 ]
Luangsa-ard, J. Jennifer [1 ]
Prabpai, Samran [2 ,3 ]
Kongsaeree, Palangpon [2 ,3 ]
机构
[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Klongluang 12120, Pathumthani, Thailand
[2] Mahidol Univ, Dept Chem, Bangkok 10400, Thailand
[3] Mahidol Univ, Ctr Excellence Prot Struct & Funct, Fac Sci, Bangkok 10400, Thailand
来源
JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 10期
关键词
METABOLITES;
D O I
10.1021/np200429b
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7 beta,15 alpha-dihydroxy-22(29)-hopene (8), 3 beta,7 beta-dihydroxy-22(29)-hopene (9), 3 beta-acetoxy-15 alpha-hydroxy-22(29)-hopene (10), 3 beta,7 beta,15 alpha,22-tetrahydroxyhopane (11), 3 beta-acetoxy-7 beta,15 alpha,22-trihydroxyhopane (12), and 7 beta,15 alpha,22-trihydroxyhopane(13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.
引用
收藏
页码:2143 / 2150
页数:8
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