Maximum effect of triptans in migraine? A comment

被引：9
|
作者：
Tfelt-Hansen, P. [1 ]
机构：
[1] Univ Copenhagen, Glostrup Hosp, Dept Neurol, Danish Headache Ctr, DK-2600 Glostrup, Denmark
来源：
CEPHALALGIA | 2008年 / 28卷 / 07期
关键词：
triptans; naratriptan; maximum effect; central sensitization;
D O I：
10.1111/j.1468-2982.2007.01415.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The efficacy of triptans in the treatment of migraine was recently contested. How high is then the maximum effect of a triptan? After subcutaneous naratriptan 10 mg a 88% pain-free response was observed. This result was obtained despite the fact that more half of the patients had a migraine duration of > 4 h. These results indicate that subcutaneous naratriptan in a high dose can overcome central sensitization that occurs in migraine attacks.
引用
收藏
页码：767 / 768
页数：2
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