A 47-year-old woman was admitted to our hospital because of severe low back pain, A computed tomography (CT) scan revealed a left sided psoas muscle abscess. On the first hospital day, US-guided drainage was performed, Streptococcus pneumoniae was isolated from the pus. Thereafter, the open drainkage of the abscess and antibiotic treatment were given with subsequent clinical improvement. Only 10 cases of pneumococcal psoas abscess have been previously reported in the world literature.