Interstitial lung disease after receiving the mRNA-based COVID-19 vaccine tozinameran

被引：4
|
作者：
Oda, Naohiro [1 ]
Mitani, Reo [1 ]
Takata, Ichiro [1 ]
Kataoka, Mikio [2 ]
机构：
[1] Fukuyama City Hosp, Dept Internal Med, 5-23-1 Zao Cho, Fukuyama, Hiroshima 7218511, Japan
[2] Onomichi Municipal Hosp, Dept Resp Med, Onomichi, Japan
来源：
RESPIRATORY MEDICINE CASE REPORTS | 2022年 / 36卷
关键词：
D O I：
10.1016/j.rmcr.2022.101618
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Tozinameran, a messenger ribonucleic acid (mRNA)-based coronavirus disease 19 (COVID-19) vaccine, has a favorable safety profile and is highly efficacious in preventing COVID-19. Adverse reactions such as pain at the vaccination site, fever, malaise, headache, rash, and anaphylaxis have been commonly reported for mRNA-based COVID-19 vaccines. We report a case involving a 71-year-old Japanese woman who developed interstitial lung disease (ILD) after receiving an mRNA-based COVID-19 vaccine. We also review case reports of COVID-19 mRNA vaccine-associated ILD. Dyspnea or hypoxia that develops within 1-3 days after COVID-19 mRNA vaccination should be differentiated from ILD. Further studies to elucidate mechanisms and risk factors of rare adverse reactions such as ILD are warranted.
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页数：5
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