Diagnosis and management of hereditary angioedema: an American approach

被引:33
|
作者
Zuraw, BL [1 ]
机构
[1] Scripps Res Inst, Dept Mol & Expt Med, La Jolla, CA 92037 USA
关键词
HAE; C1; inhibitor; anabolic androgens; epsilon aminocaproic acid;
D O I
10.1016/j.transci.2003.08.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of angioedema. and caused by a deficiency of the plasma protein Cl inhibitor. HAE attacks carry a substantial risk of morbidity or even mortality, making it imperative that the correct diagnosis be established and an appropriate management plan be in place. This report reviews the current diagnostic and therapeutic approaches available in the United States. Areas in which the diagnostic or therapeutic tools are deficient are discussed, and the prospects for improved therapeutic modalities highlighted. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:239 / 245
页数:7
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