Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of angioedema. and caused by a deficiency of the plasma protein Cl inhibitor. HAE attacks carry a substantial risk of morbidity or even mortality, making it imperative that the correct diagnosis be established and an appropriate management plan be in place. This report reviews the current diagnostic and therapeutic approaches available in the United States. Areas in which the diagnostic or therapeutic tools are deficient are discussed, and the prospects for improved therapeutic modalities highlighted. (C) 2003 Elsevier Ltd. All rights reserved.
机构:
Winthrop Univ Hosp, Div Rheumatol Immunol & Allergy, Mineola, NY 11501 USAWinthrop Univ Hosp, Div Rheumatol Immunol & Allergy, Mineola, NY 11501 USA
机构:
Kaiser Permanente, Dept Allergy, San Diego, CA USA
Univ Calif San Diego, San Diego, CA 92103 USAKaiser Permanente, Dept Allergy, San Diego, CA USA
Christiansen, Sandra C.
Zuraw, Bruce L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
San Diego Vet Affairs Med Ctr, La Jolla, CA USAKaiser Permanente, Dept Allergy, San Diego, CA USA
机构:
Penn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USAPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Craig, Timothy
Pueruesn, Emel Aygoeren
论文数: 0引用数: 0
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机构:
Goethe Univ Frankfurt, Ctr Pediat & Juvenile Med, Frankfurt, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Pueruesn, Emel Aygoeren
Bork, Konrad
论文数: 0引用数: 0
h-index: 0
机构:
Johannes Gutenberg Univ Mainz, Dept Dermatol, Mainz, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Bork, Konrad
Bowen, Tom
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calgary, Dept Med, Calgary, AB, Canada
Univ Calgary, Dept Pediat, Calgary, AB, CanadaPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Bowen, Tom
Boysen, Henrik
论文数: 0引用数: 0
h-index: 0
机构:
HAEi, Orsay, FrancePenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Boysen, Henrik
Farkas, Henriette
论文数: 0引用数: 0
h-index: 0
机构:
Semmelweis Univ, Dept Internal Med 3, Budapest, HungaryPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Farkas, Henriette
Grumach, Anete
论文数: 0引用数: 0
h-index: 0
机构:
Fac Med ABC, Outpatient Grp Recurrent Infect & Lab Immunol, Sao Paulo, Brazil
Univ Sao Paulo, Fac Med, Dept Dermatol, Sao Paulo, BrazilPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Grumach, Anete
Katelaris, Constance H.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Western Sydney, Campbelltown Hosp, Dept Med, Sydney, NSW, AustraliaPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Katelaris, Constance H.
Lockey, Richard
论文数: 0引用数: 0
h-index: 0
机构:
Univ S Florida, Allergy Asthma & Immunol Associates Tampa Bay, Tampa, FL USAPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Lockey, Richard
Longhurst, Hilary
论文数: 0引用数: 0
h-index: 0
机构:
Barts Hlth NHS Trust, Dept Immunol, London, EnglandPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Longhurst, Hilary
Lumry, William
论文数: 0引用数: 0
h-index: 0
机构:
Allergy & Asthma Specialists, Dallas, TX USAPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Lumry, William
Magerl, Markus
论文数: 0引用数: 0
h-index: 0
机构:
Charite, Allergie Ctr Charite, Dept Dermatol & Allergy, Charitepl 1, D-10117 Berlin, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Magerl, Markus
Martinez-Saguer, Immaculada
论文数: 0引用数: 0
h-index: 0
机构:
Goethe Univ Frankfurt, Ctr Pediat & Juvenile Med, Frankfurt, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Martinez-Saguer, Immaculada
Ritchie, Bruce
论文数: 0引用数: 0
h-index: 0
机构:
Univ Alberta, Dept Med, Edmonton, AB, CanadaPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Ritchie, Bruce
Nast, Alexander
论文数: 0引用数: 0
h-index: 0
机构:
Charite, Allergie Ctr Charite, Dept Dermatol & Allergy, Charitepl 1, D-10117 Berlin, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Nast, Alexander
Pawankar, Ruby
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h-index: 0
机构:
Nippon Med Sch, Dept Pediat, Div Allergy, Tokyo, JapanPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Pawankar, Ruby
Zuraw, Bruce
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Med, Med, La Jolla, CA 92093 USA
San Diego VA Healthcare, San Diego, CA USAPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Zuraw, Bruce
Maurer, Marcus
论文数: 0引用数: 0
h-index: 0
机构:
Charite, Allergie Ctr Charite, Dept Dermatol & Allergy, Charitepl 1, D-10117 Berlin, GermanyPenn State Univ, Dept Med Pediat & Grad Studies, Hershey, PA USA
Maurer, Marcus
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2012,
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