Inhibitors of the ras signal transduction pathway as potential antitumour agents

被引：8
|
作者：
Perrin, D [1 ]
Halazy, S [1 ]
Hill, BT [1 ]
机构：
[1] CTR RECH PIERRE FABRE,DIV CANCEROL EXPT,F-81106 CASTRES,FRANCE
来源：
JOURNAL OF ENZYME INHIBITION | 1996年 / 11卷 / 02期
关键词：
Ras; farnesyl-protein transferase; Ras signalling pathway; farnesyl-protein transferase inhibitors; antitumour activity; Ras processing;
D O I：
10.3109/14756369609036536
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：77 / 95
页数：19
相关论文
共 50 条
  • [21] THE ROLE OF RAS IN SIGNAL TRANSDUCTION
    JOHNSTON, C
    MORRIS, J
    HALL, A
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1991, 19 (02) : 296 - 299
  • [22] Ras, superoxide and signal transduction
    Irani, K
    Goldschmidt-Clermont, PJ
    BIOCHEMICAL PHARMACOLOGY, 1998, 55 (09) : 1339 - 1346
  • [23] Visualization of signal transduction of Ras
    Ohba, Y
    Matsuda, M
    SEIKAGAKU, 2004, 76 (01): : 16 - 28
  • [24] Intricacies of Ras signal transduction
    Moodie, SA
    Paris, M
    Hamilton, M
    Wolfman, A
    JOURNAL OF NEUROCHEMISTRY, 1996, 66 : S55 - S55
  • [25] Signal transduction via Ras
    Wittinghofer, A
    BIOLOGICAL CHEMISTRY, 1998, 379 (8-9) : 933 - 937
  • [26] Modulation of the ERK pathway of signal transduction by cysteine proteinase inhibitors
    Torres, C
    Li, M
    Walter, R
    Sierra, F
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2000, 80 (01) : 11 - 23
  • [27] TRIACRIDINES AS POTENTIAL ANTITUMOUR AGENTS
    ATWELL, GJ
    LEUPIN, W
    TWIGDEN, SJ
    DENNY, WA
    NEW ZEALAND MEDICAL JOURNAL, 1984, 97 (757) : 373 - 373
  • [28] RAF FUNCTIONS DOWNSTREAM OF RAS1 IN THE SEVENLESS SIGNAL TRANSDUCTION PATHWAY
    DICKSON, B
    SPRENGER, F
    MORRISON, D
    HAFEN, E
    NATURE, 1992, 360 (6404) : 600 - 603
  • [29] Inhibitors of tyrosine kinase proteins induced Ras signaling pathway as potential anti-tumor agents
    Vidal, M
    Liu, WQ
    Gril, B
    Lenoir, C
    Garbay, C
    COMPTES RENDUS CHIMIE, 2005, 8 (05) : 815 - 821
  • [30] The Drosophila secreted protein argos regulates signal transduction in the Ras/MAPK pathway
    Sawamoto, K
    Okabe, M
    Tanimura, T
    Mikoshiba, K
    Nishida, Y
    Okano, H
    DEVELOPMENTAL BIOLOGY, 1996, 178 (01) : 13 - 22
12345