A rhodamine-based fluorescent probe containing a Se-N bond for detecting thiols and its application in living cells

被引：394
|
作者：
Tang, Bo [1 ]
Xing, Yanlong
Li, Ping
Zhang, Ning
Yu, Fabiao
Yang, Guiwen
机构：
[1] Shandong Normal Univ, Coll Med, Engn Res Ctr Pesticide & Med Intermediate, Minist Educ, Jinan 250014, Peoples R China
[2] Shandong Normal Univ, Coll Life Sci, Jinan 250014, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 38期
关键词：
D O I：
10.1021/ja072572q
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Here we report a new rhodamine-based fluorescent probe containing a selenium-nitrogen bond for detecting thiols based on the nucleophilic substitution of sulfhydryl. The probe was successfully applied to the imaging of thiols in both HL-7702 cells and HepG2 cells with high sensitivity and selectivity.
引用
收藏
页码：11666 / +
页数：3
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