Low cytotoxicity rhodamine-based fluorescent probes for Fe(III) and their application in living cells

被引：21
|
作者：
Liu, Xiao-Jing [1 ]
Zhang, Ming [1 ]
Yang, Mei-Pan [1 ]
Li, Bo [1 ]
Cheng, Zhao [2 ]
Yang, Bing-Qin [1 ]
机构：
[1] Northwest Univ, Coll Chem & Mat Sci, Key Lab Synthet & Nat Funct Mol Chem, Minist Educ, Xian 710127, Shaanxi, Peoples R China
[2] Xian Med Univ, Sch Pharmaceut Sci, Xian 710021, Shaanxi, Peoples R China
来源：
TETRAHEDRON | 2015年 / 71卷 / 42期
基金：
中国国家自然科学基金;
关键词：
Rhodamine B; Fluorescent probe; Recognition; Low toxicity; Live cell imaging; IRON; CHEMOSENSOR; FE3+; IRON(III); COUMARIN;
D O I：
10.1016/j.tet.2015.08.031
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two novel rhodamine-active probes G2 and R2 were designed and synthesized, which adopted a 1:1 binding stoichiometry and showed highly selective sensing for Fe3+ ions over other metal ions in EtOH-H2O (1:1, v/v, Tris-HCl pH=7.4) in the fluorescence and ultraviolet spectra. Cytotoxicity and bioimaging studies by PC12 and L929 indicated that the probes were low cytotoxic, cell permeable and suitable for detecting Fe3+ in living cells. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：8194 / 8199
页数：6
相关论文
共 50 条
  • [1] A naked-eye rhodamine-based fluorescent probe for Fe(III) and its application in living cells
    Wang, Shuxin
    Meng, Xiangming
    Zhu, Manzhou
    TETRAHEDRON LETTERS, 2011, 52 (22) : 2840 - 2843
  • [2] Rhodamine-Based Fluorescent Probes for Cations
    Yuan Yuehua
    Tian Maozhong
    Feng Feng
    Meng Shuangming
    Bai Yunfeng
    PROGRESS IN CHEMISTRY, 2010, 22 (10) : 1929 - 1939
  • [3] Rhodamine-Based Fluorescent Probes for Cations
    Li Junbo
    Hu Qihui
    Zeng Yang
    Yu Xianglin
    Pan Zhiquan
    PROGRESS IN CHEMISTRY, 2012, 24 (05) : 823 - 833
  • [4] Application of rhodamine-based fluorescent molecular probes in visualization of cellular pyruvic acid
    Wang Shuo
    Sun Xiaoyan
    Chen Jinlong
    JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY, 2018, 49 (01) : 79 - 86
  • [5] Rhodamine-based fluorescent sensor for mercury in buffer solution and living cells
    Wang, Huan-Huan
    Xue, Lin
    Yu, Cai-Lan
    Qian, Yuan-Yu
    Jiang, Hua
    DYES AND PIGMENTS, 2011, 91 (03) : 350 - 355
  • [6] A new rhodamine-based fluorescent chemosensor for Fe3+ and its application in living cell imaging
    Li, Chun-Yan
    Zou, Chun-Xiang
    Li, Yong-Fei
    Tang, Jia-Liang
    Weng, Chao
    DYES AND PIGMENTS, 2014, 104 : 110 - 115
  • [7] Study of Rhodamine-Based Fluorescent Probes for Organic Radical Intermediates
    He, Jiaxin
    Yan, Boyu
    Meng, Jiangtao
    Ran, Maogang
    Zhou, Yutong
    Deng, Jinfei
    Li, Chao-Jun
    Yao, Qiuli
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 2021 (29) : 4059 - 4064
  • [8] Recent Progress in Rhodamine-Based "OFF-ON" Fluorescent Probes
    Li, Na
    Liu, Meiling
    Yin, Wenting
    Yang, Zheng
    Li, Jianli
    Shi, Zhen
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 31 (01) : 39 - 53
  • [9] Rhodamine-based fluorescent probes for selective detection of glutathione and cysteine
    Ming, Wei
    Feng, Jingjing
    Chang, Shunzhou
    Xiang, Kaiqiang
    Liu, Ziyan
    Tian, Baozhu
    Zhang, Jinlong
    RESEARCH ON CHEMICAL INTERMEDIATES, 2017, 43 (12) : 7387 - 7398
  • [10] Rhodamine-based fluorescent probes for selective detection of glutathione and cysteine
    Wei Ming
    Jingjing Feng
    Shunzhou Chang
    Kaiqiang Xiang
    Ziyan Liu
    Baozhu Tian
    Jinlong Zhang
    Research on Chemical Intermediates, 2017, 43 : 7387 - 7398
12345