The utility of marginal donors in liver transplantation

被引：555
|
作者：
Busuttil, RW
Tanaka, K
机构：
[1] Dumont UCLA Transplant Ctr, Div Liver & Pancreas Transplantat, Dept Surg, Los Angeles, CA 90095 USA
[2] Kyoto Univ, Dept Surg, Kyoto, Japan
来源：
LIVER TRANSPLANTATION | 2003年 / 9卷 / 07期
关键词：
D O I：
10.1053/jlts.2003.50105
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The shortage, of organs has led centers to expand their criteria for the acceptance of marginal donors. The combination of multiple marginal factors seems to be additive on graft injury. In this review, the utility of various marginal donors in patients requiring liver transplantation will be described, including older donors, steatotic livers, non-heart-beating donors, donors with viral hepatitis; and donor's with malignancies. The pathophysiology of the marginal donor will be discussed, along with strategies for minimizing the ischemia reperfusion injury experienced by these organs. Finally, new strategies for improving the function of the marginal/expanded donor liver will be reviewed.
引用
收藏
页码：651 / 663
页数：13
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