Cognitive impairment associated with major depression following mild and moderate traumatic brain injury

被引：119
|
作者：
Rapoport, MJ
McCullagh, S
Shammi, P
Feinstein, A
机构：
[1] Univ Toronto, Sunnybrook & Womens Coll Hlth Sci Ctr, Dept Psychiat, Toronto, ON M4N 3M5, Canada
[2] Univ Toronto, Sunnybrook & Womens Coll Hlth Sci Ctr, Traumat Brain Injury Clin, Toronto, ON M4N 3M5, Canada
[3] Baycrest Ctr Geriatr Care, Dept Psychol, Toronto, ON, Canada
来源：
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2005年 / 17卷 / 01期
关键词：
D O I：
10.1176/appi.neuropsych.17.1.61
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Traumatic brain injury (TBI) and major depression are neuropsychiatric conditions that have been associated with cognitive dysfunction. The aim of this study was to explore the relationship between major depression and cognitive impairment following mild and moderate TBI. Seventy-four TBI patients were assessed for the presence of major depression using the Structured Clinical Interview for the DSM-IV and completed a neurocognitive assessment battery. Subjects with major depression (28.4%), compared to those without, were found to have significantly lower scores on measures of working memory, processing speed, verbal memory and executive function. Potential mechanisms and implications for treatment are discussed.
引用
收藏
页码：61 / 65
页数：5
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