Two-Higgs-doublet models (2HDMs) with a flavored U(1)' gauge symmetry are a popular extension to the Standard Model (SM), yet they currently lack a complete survey. In this paper, we present a full classification of anomaly-free 2HDMs within the SM fermion content, resulting in a total of 11 distinct models. Four of these are relatively well studied, while the rest either partially, or entirely, lack previous treatment. We study these textures under a variety of experimental bounds, focusing mainly on the previously unexplored models. This work is intended to act as a catalog to models worth considering in greater detail.