The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review

被引：10
|
作者：
Bullert, Amanda J. [1 ,2 ]
Doorn, Jonathan A. [1 ,2 ]
Stevens, Hanna E. [1 ,3 ]
Lehmler, Hans-Joachim [1 ,2 ]
机构：
[1] Univ Iowa, Interdisciplinary Grad Program Neurosci, Iowa City, IA 52242 USA
[2] Univ Iowa, Dept Occupat & Environm Hlth, Iowa City, IA 52242 USA
[3] Univ Iowa, Dept Psychiat, Iowa City, IA 52242 USA
来源：
CHEMICAL RESEARCH IN TOXICOLOGY | 2021年 / 34卷 / 09期
基金：
美国国家卫生研究院;
关键词：
2-HIT EXPOSURE; RELIABILITY; RATS;
D O I：
10.1021/acs.chemrestox.1c00226
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Exposure to polychlorinated biphenyls (PCBs) is implicated in adverse neurotoxic outcomes. However, the impact of PCBs on the adolescent nervous system has received inadequate attention. We conducted a comprehensive review to identify studies of neurotoxic outcomes following PCB exposure during the adolescent period in rodents. Only four papers were found to meet all inclusion criteria. PCB exposure in adolescent rats caused disruptions in the main functions of the prefrontal cortex, resulting in cognitive deficits. This comprehensive review demonstrates that more research is needed to characterize how PCB exposure adversely affects the adolescent nervous system.
引用
收藏
页码：1948 / 1952
页数：5
相关论文
共 50 条
  • [31] Effects of Ethanol Exposure During Adolescence or Adulthood on Locomotor Sensitization and Dopamine Levels in the Reward System
    Carrara-Nascimento, Priscila Fernandes
    Hoffmann, Lucas Barbosa
    Florio, Jorge Camilo
    Planeta, Cleopatra Silva
    Camarini, Rosana
    FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2020, 14
  • [32] New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence
    Schor, Nina F.
    PHARMACOLOGY & THERAPEUTICS, 2009, 122 (01) : 44 - 55
  • [33] Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation
    Pocar, P
    Nestler, D
    Risch, M
    Fischer, B
    REPRODUCTION, 2005, 130 (06) : 857 - 868
  • [34] Polychlorinated biphenyl accumulation differs among pumpkinseed sunfish during experimental field exposure: the role of invertebrate prey
    Feldman, RS
    Titus, JE
    AQUATIC TOXICOLOGY, 2001, 51 (04) : 389 - 404
  • [35] ULTRASTRUCTURAL FEATURES OF THE MICRO-CIRCULATORY SYSTEM OF MURINE PINNAE AFTER EXPOSURE TO POLYCHLORINATED BIPHENYL COMPOUNDS (PCBS)
    BELL, M
    CLINICAL RESEARCH, 1979, 27 (02): : A522 - A522
  • [36] Polychlorinated biphenyl exposure delays metamorphosis and alters thyroid hormone system gene expression in developing Xenopus laevis
    Shirey, Elisabeth A. Lehigh
    Langerveld, Anna Jelaso
    Mihalko, Daniel
    Ide, Charles F.
    ENVIRONMENTAL RESEARCH, 2006, 102 (02) : 205 - 214
  • [37] Behavioural effects in female rats of postnatal exposure to sub-toxic doses of polychlorinated biphenyl congener 153
    Holene, E
    Nafstad, I
    Skaare, JU
    Krogh, H
    Sagvolden, T
    ACTA PAEDIATRICA, 1999, 88 : 55 - 63
  • [38] Effects of exposure to violence with a weapon during adolescence on adult hypertension
    Ford, Jodi L.
    Browning, Christopher R.
    ANNALS OF EPIDEMIOLOGY, 2014, 24 (03) : 193 - 198
  • [39] Effects of polychlorinated biphenyls exposure on physical growth from birth to childhood and adolescence: A prospective cohort study
    Tahir, Emad
    Cordier, Sylvaine
    Courtemanche, Yohann
    Forget-Dubois, Nadine
    Desrochers-Couture, Mireille
    Belanger, Richard E.
    Ayotte, Pierre
    Jacobson, Joseph L.
    Jacobson, Sandra W.
    Muckle, Gina
    ENVIRONMENTAL RESEARCH, 2020, 189
  • [40] Effects of Ethanol Exposure on Nervous System Development in Zebrafish
    Cole, Gregory J.
    Zhang, Chengjin
    Ojiaku, Princess
    Bell, Vanessa
    Devkota, Shailendra
    Mukhopadhyay, Somnath
    INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 299, 2012, 299 : 255 - 315
12345