Enhanced Liver Fibrosis Score Stratifies Hepatocellular Carcinoma Risk in Patients With Hepatitis B Surface Antigen Seroclearance

被引：3

作者：

Mak, Lung-Yi ^{[1
,2
]}

Cheung, Ka-Shing ^{[1
,3
]}

Hui, Rex Wan-Hin ^{[1
]}

Wong, Danny Ka-Ho ^{[1
,2
]}

Fung, James ^{[1
,2
]}

Yuen, Man-Fung ^{[1
,2
]}

Seto, Wai-Kay ^{[1
,2
,3
]}

机构：

[1] Univ Hong Kong, Queen Mary Hosp, Dept Med, Pokfulam Rd 102, Hong Kong, Peoples R China

[2] Univ Hong Kong, State Key Lab Liver Res, Hong Kong, Peoples R China

[3] Univ Hong Kong, Dept Med, Shenzhen Hosp, Shenzhen, Peoples R China

来源：

CLINICAL INFECTIOUS DISEASES | 2022年 / 75卷 / 12期

关键词：

hepatitis B virus (HBV); enhanced liver fibrosis (ELF); functional cure; hepatocellular carcinoma ( HCC); HBSAG SEROCLEARANCE;

D O I：

10.1093/cid/ciac387

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this prospective study involving 337 chronic hepatitis B patients who achieved spontaneous hepatitis B surface antigen (HBsAg) seroclearance (SC), serum enhanced liver fibrosis (ELF) before SC was associated with hepatocellular carcinoma (HCC) (hazard ratio 2.588), and ELF 97% reduction in risk of HCC development in patients with age SC >= 50 (n = 190).

引用

页码：2257 / 2259

页数：3

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