No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience

被引：16
|
作者：
Box, Maggie J. [1 ]
Ortwine, Kristine N. [1 ]
Goicoechea, Miguel [2 ]
机构：
[1] Scripps Hlth, Dept Pharm, San Diego, CA USA
[2] Scripps Hlth, Div Infect Dis, San Diego, CA USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2018年 / 5卷 / 12期
关键词：
Clostridium difficile infection; hospitalized patients; probiotics; ANTIBIOTIC-ASSOCIATED DIARRHEA; PREVENTION; ADULTS;
D O I：
10.1093/ofid/ofy192
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility-onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P =.16).
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页数：3
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