No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience

被引：16

作者：

Box, Maggie J. ^{[1
]}

Ortwine, Kristine N. ^{[1
]}

Goicoechea, Miguel ^{[2
]}

机构：

[1] Scripps Hlth, Dept Pharm, San Diego, CA USA

[2] Scripps Hlth, Div Infect Dis, San Diego, CA USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2018年 / 5卷 / 12期

关键词：

Clostridium difficile infection; hospitalized patients; probiotics; ANTIBIOTIC-ASSOCIATED DIARRHEA; PREVENTION; ADULTS;

D O I：

10.1093/ofid/ofy192

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility-onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P =.16).

引用

页数：3

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