Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect

被引：14

作者：

Liu, Shengda ^{[1
]}

Tian, Ruizhen ^{[1
]}

Xu, Jiayun ^{[1
]}

Wang, Liang ^{[1
]}

Sun, Jianxin ^{[1
]}

Jiang, Xiaojia ^{[1
]}

Wang, Tingting ^{[1
]}

Li, Xiumei ^{[1
]}

Luo, Quan ^{[1
]}

Liu, Junqiu ^{[1
]}

机构：

[1] Jilin Univ, State Key Lab Supramol Struct & Mat, Coll Chem, Changchun 130012, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 92期

基金：

中国国家自然科学基金;

关键词：

GLUTATHIONE-PEROXIDASE; SUPEROXIDE-DISMUTASE; CONSTRUCTION; MICROGEL; NANOZYME; ENZYMES;

D O I：

10.1039/c9cc07085k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A supramolecular nanocapsule was constructed by the ternary host-guest complexation of azobenzene (Azo) and methylviologen (MV) to cucurbit[8]uril (CB[8]) and the subsequent self-assembly. The supramolecular nanocapsule with both glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities can mimic the intracellular enzymatic reactive oxygen species (ROS) defense system.

引用

页码：13820 / 13823

页数：4

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