A remarkable iodine-catalyzed protection of carbonyl compounds

被引:68
|
作者
Banik, BK [1 ]
Chapa, M [1 ]
Marquez, J [1 ]
Cardona, M [1 ]
机构
[1] Univ Texas Pan Amer, Dept Chem, Edinburg, TX 78541 USA
关键词
D O I
10.1016/j.tetlet.2005.01.176
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report here a remarkably simple molecular iodine-catalyzed protection method for various carbonyl Compounds as ketals in a general reaction. The iodine-catalyzed reaction of mandelic acid and lactic acid with several aldehydes has furnished a highly diastereoselective synthesis of cis and trans dioxolanones. (c) 2005 Published by Elsevier Ltd.
引用
收藏
页码:2341 / 2343
页数:3
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