An efficient and greener approach to the synthesis of 3,5-dicyanopyridin-2 (1H)-one derivatives in aqueous media under microwave irradiation conditions

被引:8
|
作者
Jia, Runhong
Tu, Shujiang [1 ]
Zhang, Yan
Jiang, Bo
Zhang, Junyong
Yao, Changsheng
Shi, Feng
机构
[1] Lianyungang Teachers Coll, Jiangsu 222006, Peoples R China
[2] Xuzhou normal Univ, Coll Chem & Chem Engn, Xuzhou 221116, Peoples R China
关键词
D O I
10.1002/jhet.5570440533
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile and greener synthesis of a series of 3,5-dicyanopyridin-2(1H)-one derivatives was accomplished via the one-pot reaction of aldehyde, malononitrile and sodium hydroxide in aqueous media under microwave irradiation. This method had several advantages such as shorter route and time, lower cost, reduced environmental impact.
引用
收藏
页码:1177 / 1180
页数:4
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