A Comprehensive Review of Current Perspectives on Novel Drug Delivery Systems and Approaches for Lung Cancer Management

Cancer is one of the fatal diseases that cause many deaths around the world. Lung cancer has the highest incidence and mortality rates among cancer-related death worldwide. Lung cancer is a common malignant tumor that poses a severe threat to human life due to its high prevalence and mortality. There are no early screening biomarkers for lung cancer. Patients with lung cancer are often diagnosed in the middle and advanced stages of the disease that show unfavorable clinical outcomes. Chemotherapy, radiation therapy, and surgical removal are commonly used to cure lung cancer. Chemotherapy is among the most common techniques for treating lung cancer. Due to the incredibly low delivery potency and non-specificity of anti-cancer medications, systematic chemotherapy is limited in clinical effectiveness and has significant toxic side effects. Despite continued medical advances, lung cancer nevertheless needs successful treatment. Nanotechnology has recently emerged as a potential approach to lung cancer management and care. Present therapies have been transformed by nanotechnology, which focuses on reducing toxicity and enhancing the bioavailability of anticancer medications in tumor cells. However, nanotechnology would have to tackle many challenges to gain traction in lung cancer treatment. This article reviews the latest literature on the use of nano-drug delivery mechanisms in lung cancer treatment. This research aims to propose new ideas for developing nanocarriers for lung cancer drug delivery.