DNA vaccines and apoptosis: to kill or not to kill?

被引：19

作者：

Leitner, WW ^{[1
]}

Restifo, NP ^{[1
]}

机构：

[1] NCI, Surg Branch, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2003年 / 112卷 / 01期

关键词：

D O I：

10.1172/JCI200319069

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The apoptotic machinery has become the latest target of vaccinologists attempting to improve the efficacy of DNA vaccines. While workers have previously sought to induce apoptotic death in transfected DCs as a means to activate immunity, a new approach (see related article on pages 109-117) instead seeks to delay apoptosis in host DCs after DNA vaccination.

引用

页码：22 / 24

页数：3

共 50 条

[21] PCR - HOW TO KILL UNWANTED DNA
PRINCE, AM
ANDRUS, L
BIOTECHNIQUES, 1992, 12 (03) : 358 - &
[22] Loopholes in the DNA contract kill neurons
Herrup, Karl
Tse, Kai-Hei
Chow, Hei-Man
NATURE NEUROSCIENCE, 2017, 20 (09) : 1192 - 1194
[23] Lipids, cardiolipin and apoptosis: a greasy licence to kill
Esposti, MD
CELL DEATH AND DIFFERENTIATION, 2002, 9 (03): : 234 - 236
[24] IGFBP-3 and apoptosis -: a licence to kill?
Butt, AJ
Williams, AC
APOPTOSIS, 2001, 6 (03) : 199 - 205
[25] Harnessing apoptosis to kill breast cancer cells
Letai, A.
CANCER RESEARCH, 2009, 69 (02) : 61S - 61S
[26] Lipids, cardiolipin and apoptosis: a greasy licence to kill
M Degli Esposti
Cell Death & Differentiation, 2002, 9 : 234 - 236
[27] To kill or not to kill: A question of wartime ethics
Williams, PT
NURSING ETHICS, 1996, 3 (02) : 150 - 156
[28] Natural killer cells:: to kill or not to kill
Schleinitz, N
Lopez, F
Vivier, É
Vely, F
M S-MEDECINE SCIENCES, 2001, 17 (04): : 504 - 509
[29] Lange 'Faster Pussycat! Kill!...Kill!'
Meyer-Arlt, R
THEATER HEUTE, 2001, (05): : 43 - 43
[30] BRAIN LATERALIZATION OF MURICIDE - TO KILL OR NOT TO KILL
GALL, JS
BERREBI, AS
HOFMANN, MB
YUTZEY, DA
DENENBERG, VH
AGGRESSIVE BEHAVIOR, 1985, 11 (02) : 140 - 140

← 1 2 3 4 5 →