Evidence based guidelines for the treatment of Helicobacter pylori infection in Korea 2020

被引：15

作者：

Jung, Hye-Kyung ^{[1
]}

Kang, Seung Joo ^{[2
]}

Lee, Yong Chan ^{[3
]}

Yang, Hyo-Joon ^{[4
,5
]}

Park, Seon-Young ^{[6
]}

Shin, Cheol Min ^{[7
]}

Kim, Sung Eun ^{[8
]}

Lim, Hyun Chul ^{[9
]}

Kim, Jie-Hyun ^{[3
,10
]}

Nam, Su Youn ^{[11
]}

Shin, Woon Geon ^{[12
]}

Park, Jae Myung ^{[13
]}

Choi, Il Ju ^{[14
]}

Kim, Jae Gyu ^{[15
]}

Choi, Miyoung ^{[16
]}

机构：

[1] Ewha Womans Univ, Sch Med, Dept Internal Med, Seoul, South Korea

[2] Seoul Natl Univ Hosp Healthcare, Dept Internal Med, Seoul, South Korea

[3] Yonsei Univ, Coll Med, Dept Internal Med, 50-1 Yonsei Ro, Seoul 03722, South Korea

[4] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Div Gastroenterol,Dept Internal Med, Seoul, South Korea

[5] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Gastrointestinal Canc Ctr, Seoul, South Korea

[6] Chonnam Natl Univ, Med Sch, Dept Internal Med, Gwangju, South Korea

[7] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea

[8] Kosin Univ, Coll Med, Dept Internal Med, Busan, South Korea

[9] Yonsei Univ, Yongin Severance Hosp, Dept Internal Med, Coll Med, Yongin, South Korea

[10] Yonsei Univ, Coll Med, Inst Gastroenterol, Seoul, South Korea

[11] Kyungpook Natl Univ, Chilgok Hosp, Ctr Gastr Canc, Daegu, South Korea

[12] Hallym Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[13] Catholic Univ Korea, Coll Med, Dept Internal Med, Div Gastroenterol & Hepatol,Seoul St Marys Hosp, Seoul, South Korea

[14] Natl Canc Ctr, Ctr Gastr Canc, Goyang, South Korea

[15] Chung Ang Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[16] Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, Seoul, South Korea

来源：

KOREAN JOURNAL OF INTERNAL MEDICINE | 2021年 / 36卷 / 04期

关键词：

Helicobacter pylori; Guidelines; Treatment; Meta-analysis; Microbial sensitivity tests; STANDARD TRIPLE THERAPY; PROTON-PUMP INHIBITOR; RANDOMIZED CLINICAL-TRIAL; 10-DAY SEQUENTIAL THERAPY; QUADRUPLE CONCOMITANT THERAPY; DOSE DUAL THERAPY; IRON-DEFICIENCY ANEMIA; FUNCTIONAL DYSPEPSIA; RESCUE THERAPY; BISMUTH QUADRUPLE;

D O I：

10.3904/kjim.2020.701

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Helicobacter pylori infection is one of the most common infectious diseases worldwide. H. pylori is responsible for substantial gastrointestinal morbidity with a high disease burden. Since the revision of the H. pylori Clinical Practice Guidelines in 2013 in Korea, the eradication rate of H. pylori has gradually decreased with the use of a clarithromycin based triple therapy. According to a nationwide randomized controlled study by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance to clarithromycin. The clinical practice guidelines for treatment of H. pylori were updated based on evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after expert consensus on three recommendations regarding the indication for treatment and eight recommendations on the treatment itself. These guidelines were designed to provide clinical evidence for the treatment of H. pylori to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards, and will be revised if more evidence emerges in the future.

引用

页码：807 / +

页数：56

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