A flip-flop switch in polarity signaling

被引：2
|
作者：
Menon, Anant K. [1 ]
机构：
[1] Weill Cornll Med Coll, Dept Biochem, New York, NY 10065 USA
来源：
DEVELOPMENTAL CELL | 2007年 / 13卷 / 05期
关键词：
D O I：
10.1016/j.devcel.2007.10.008
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The Rho GTPase Cdc42 is essential for polarized growth of budding yeast. Temporal control of Cdc42 depends partly on the activity of its GTPase-activating proteins (GAPs). In this issue of Developmental Cell, Saito et al. report that Cdc42 GAP activity is regulated by the phospholipid composition of the bud-tip membrane, under control of the phospholipid flippases Lem3-Dnf1 and Lem3-Dnf2.
引用
收藏
页码：607 / 608
页数：2
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