Syntheses and effectiveness of functional peptide-based RAFT agents

被引：16
|
作者：
Chen, Chao [1 ]
Kong, Fanxing [1 ]
Wei, Xiaohu [1 ]
Thang, San H. [1 ,2 ]
机构：
[1] Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China
[2] Monash Univ, Sch Chem, Clayton Campus, Clayton, Vic 3800, Australia
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 78期
关键词：
LIVING RADICAL POLYMERIZATION; BLOCK-COPOLYMERS; DRUG-DELIVERY; PERSPECTIVES; UPDATE; HOMOPOLYMERS; POLYMERS;
D O I：
10.1039/c7cc05316a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.
引用
收藏
页码：10776 / 10779
页数：4
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