Syntheses and effectiveness of functional peptide-based RAFT agents

被引：16

作者：

Chen, Chao ^{[1
]}

Kong, Fanxing ^{[1
]}

Wei, Xiaohu ^{[1
]}

Thang, San H. ^{[1
,2
]}

机构：

[1] Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China

[2] Monash Univ, Sch Chem, Clayton Campus, Clayton, Vic 3800, Australia

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 78期

关键词：

LIVING RADICAL POLYMERIZATION; BLOCK-COPOLYMERS; DRUG-DELIVERY; PERSPECTIVES; UPDATE; HOMOPOLYMERS; POLYMERS;

D O I：

10.1039/c7cc05316a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

引用

页码：10776 / 10779

页数：4

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