Diffuse large B cell lymphoma-related prognostic factors, Ki-67 and Bcl-6 expression levels.

被引：0
|
作者：
Xie, Rong [1 ]
Tang, Jing [1 ]
Hu, Sheng [1 ]
Jiang, Hui [1 ]
机构：
[1] Hubei Canc Hosp, Dept Oncol, Wuhan, Hubei, Peoples R China
来源：
BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 15期
关键词：
Diffuse large B cell lymphoma (DLBCL); Prognosis; Bcl-6; Ki-67; ANTITUMOR-ACTIVITY; NANOPARTICLES; DELIVERY; DRUG;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Objective: This study aims to investigate the diffuse large B cell lymphoma-related prognostic factors, Bcl-6 and Ki-67 expression levels. Methods: 67 cases of patients with diffuse large B cell lymphoma in our hospital were collected from Feb 2014 to Mar 2015. The Bcl-6 and Ki-67 expression levels in patients with diffuse large B cell lymphoma were detected using the immunohistochemical method. The related characteristics and prognosis were analyzed. Results: Statistical analysis shows that the Bcl-6 protein expression levels are not related to sex or age; Ki-67 is not related to sex but related to age. Bcl-6 is not related to lactate dehydrogenase or primary site but is related to Ann Arbor stage. Ki-67 is related to lactate dehydrogenase and Ann Arbor stage. Conclusion: The microvessel density dose, Bcl-6-positive rate and Ki-67 labelling index of diffuse large B cell lymphoma are important indexes to evaluate the prognosis of patients with diffuse large B cell lymphoma.
引用
收藏
页码：6740 / 6742
页数：3
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