Severe Hemolysis in a COVID-19 Patient with Paroxysmal Nocturnal Hemoglobinuria

被引：9

作者：

Otieno, Steve Biko ^{[1
,2
,3
]}

Altahan, Alaa ^{[1
,2
,3
]}

Kaweeta, Fnu ^{[1
]}

Karri, Saradasri ^{[1
,2
,3
]}

Alnoor, Fnu ^{[2
,4
]}

Johnson, Robert ^{[3
]}

机构：

[1] Univ Tennessee, Hlth Sci Ctr, Dept Hematol & Oncol, 19 S Manassas, Memphis, TN 38103 USA

[2] Vet Affairs Med Ctr, 1030 Jefferson Ave, Memphis, TN 38104 USA

[3] West Canc & Res Inst, 7945 Wolf River Blvd, Germantown, TN 38138 USA

[4] Univ Tennessee, Hlth Sci Ctr, Dept Pathol, 930 Madison Ave, Memphis, TN 38103 USA

来源：

CASE REPORTS IN HEMATOLOGY | 2021年 / 2021卷

关键词：

D O I：

10.1155/2021/6619177

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has been demonstrated to be able to activate complement, making patients with deficiency in negative complement regulation, such as paroxysmal nocturnal hemoglobinuria (PNH), particularly vulnerable to complement-mediated cell damage. We report a case of a patient who presented with fatigue, facial swelling, and upper respiratory infection (URI) symptoms and was found to have COVID-19 with laboratory tests showing severe hemolysis and pancytopenia secondary to PNH.

引用

页数：6

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