Traceless solid phase synthesis of 2,3-disubstituted indoles

被引：82
|
作者：
Smith, AL [1 ]
Stevenson, GI [1 ]
Swain, CJ [1 ]
Castro, JL [1 ]
机构：
[1] Merck Sharp & Dohme Res Labs, Neurosci Res Ctr, Harlow CM20 2QR, Essex, England
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 45期
关键词：
D O I：
10.1016/S0040-4039(98)01824-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the traceless solid phase synthesis of 2,3-disubstituted indoles using a THP linker and a Pd(0)-mediated annulation of 2-iodoaniline and acetylenes is reported. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8317 / 8320
页数：4
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