The Phenotype Paradox: Lessons From Natural Transcriptome Evolution on How to Engineer Plants

被引：1

作者：

Law, Justin ^{[1
]}

Ng, Kangbo ^{[2
,3
]}

Windram, Oliver P. F. ^{[1
]}

机构：

[1] Imperial Coll London, Grand Challenges Ecosyst & Environm, Ascot, Berks, England

[2] Francis Crick Inst, London, England

[3] UCL, Inst Phys Living Syst, London, England

来源：

FRONTIERS IN PLANT SCIENCE | 2020年 / 11卷

基金：

英国自然环境研究理事会;

关键词：

directed evolution; gene network analysis; synthetic biology; systems biology; breeding and genomics; REGULATORY NETWORKS; DUPLICATED GENES; ARABIDOPSIS; EXPRESSION; MAP; POLYPLOIDY; ACTIVATION; INFERENCE; SEQUENCE; FEATURES;

D O I：

10.3389/fpls.2020.00075

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Plants have evolved genome complexity through iterative rounds of single gene and whole genome duplication. This has led to substantial expansion in transcription factor numbers following preferential retention and subsequent functional divergence of these regulatory genes. Here we review how this simple evolutionary network rewiring process, regulatory gene duplication followed by functional divergence, can be used to inspire synthetic biology approaches that seek to develop novel phenotypic variation for future trait based breeding programs in plants.

引用

页数：7