A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

被引：24

作者：

Kaidar-Person, Orit ^{[1
,2
,3
]}

Dahn, Hannah M. ^{[4
]}

Nichol, Alan M. ^{[5
]}

Boersma, Liesbeth J. ^{[6
]}

de Ruysscher, Dirk ^{[6
]}

Meattini, Icro ^{[7
,8
]}

Pignol, Jean-Philippe ^{[4
]}

Aristei, Cynthia ^{[9
,10
]}

Belkacemi, Yazid ^{[11
,12
,13
,32
]}

Benjamin, Dori ^{[14
]}

Bese, Nuran ^{[15
]}

Coles, Charlotte E. ^{[16
]}

Franco, Pierfrancesco ^{[17
,18
]}

Ho, Alice Y. ^{[19
]}

Hol, Sandra ^{[20
]}

Jagsi, Reshma ^{[21
]}

Kirby, Anna M. ^{[22
]}

Marrazzo, Livia ^{[23
]}

Marta, Gustavo N. ^{[24
]}

Moran, Meena S. ^{[25
,32
]}

Nissen, Henrik D. ^{[26
]}

Strnad, Vratislav ^{[27
]}

Zissiadis, Yvonne ^{[28
]}

Poortmans, Philip M. ^{[29
,30
]}

Offersen, Birgitte, V ^{[31
]}

机构：

[1] Sheba Med Ctr, Breast Canc Radiat Therapy Unit, Ramat Gan, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[3] Maastricht Univ, GROW Sch Oncol & Dev Biol Maastro, Maastricht, Netherlands

[4] Dalhousie Univ, Dept Radiat Oncol, Halifax, NS, Canada

[5] BC Canc Vancouver, Dept Radiat Oncol, Vancouver, BC, Canada

[6] Maastricht Univ, GROW Sch Oncol, Dept Radiat Oncol Maastro, Med Ctr, Maastricht, Netherlands

[7] Univ Florence, Dept Expt & Clin Biomed Sci M Serio, Florence, Italy

[8] Azienda Osped Univ Careggi, Radiat Oncol Unit, Florence, Italy

[9] Univ Perugia, Radiat Oncol Sect, Dept Med & Surg, Perugia, Italy

[10] Perugia Gen Hosp, Perugia, Italy

[11] Univ Paris Est UPEC, Dept Radiat Oncol, Creteil, France

[12] Univ Paris Est UPEC, Henri Mondor Breast Ctr, Creteil, France

[13] INSERM Unit 955, Creteil, France

[14] Sheba Med Ctr, Dept Phys, Radiat Oncol, Ramat Gan, Israel

[15] Acibadem Mehmet Ali Aydinlar Univ, Res Inst Senol, Istanbul, Turkey

[16] Univ Cambridge, Dept Oncol, Cambridge, England

[17] Univ Piemonte Orientale, Dept Translat Med, Novara, Italy

[18] Univ Hosp Maggiore Carita, Dept Radiat Oncol, Novara, Italy

[19] Harvard Med Sch, Dept Radiat Oncol, Massachusetts Gen Hosp, Boston, MA 02115 USA

[20] Inst Verbeeten, Tilburg, Netherlands

[21] Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA

[22] Royal Marsden NHS Fdn Trust & Inst Canc Res, Dept Radiotherapy, Sutton, Surrey, England

[23] Careggi Univ Hosp, Med Phys Unit, Florence, Italy

[24] Hosp Sirio Libanes, Dept Radiat Oncol, Sao Paulo, Brazil

[25] Yale Sch Med, New Haven, CT USA

[26] Vejle Hosp, Dept Oncol, Vejle, Denmark

[27] Univ Hosp Erlangen, Dept Radiat Oncol, Erlangen, Germany

[28] Genesis Care, Hollywood Radiat Oncol, Albany, WA, Australia

[29] Iridium Netwerk, Antwerp, Belgium

[30] Univ Antwerp, Antwerp, Belgium

[31] Aarhus Univ Hosp, Dept Expt Clin Oncol, Aarhus, Denmark

[32] TRONE Transatlant Radiat Oncol Network, Paris, France

来源：

RADIOTHERAPY AND ONCOLOGY | 2021年 / 164卷

关键词：

Breast cancer; Mastectomy; Radiation therapy; PMRT; Bolus; Tissue compensator; SKIN-SPARING MASTECTOMY; CLINICAL-PRACTICE GUIDELINES; TARGET VOLUME DELINEATION; CARCINOMA-IN-SITU; LOCAL RECURRENCE; CHEST-WALL; REGIONAL RECURRENCE; PREDICTIVE FACTORS; AMERICAN-SOCIETY; RESIDUAL DISEASE;

D O I：

10.1016/j.radonc.2021.09.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Bolus serves as a tissue equivalent material that shifts the 95-100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method. (c) 2021 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 164 (2021) 115-121

引用

页码：115 / 121

页数：7

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