Monte Carlo likelihood inference for missing data models

被引:26
|
作者
Sung, Yun Ju [1 ]
Geyer, Charles J.
机构
[1] Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
[2] Univ Minnesota, Sch Stat, Minneapolis, MN 55455 USA
来源
ANNALS OF STATISTICS | 2007年 / 35卷 / 03期
关键词
asymptotic theory; Monte Carlo; maximum likelihood; generalized linear mixed model; empirical process; model misspecification;
D O I
10.1214/009053606000001389
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We describe a Monte Carlo method to approximate the maximum likelihood estimate (MLE), when there are missing data and the observed data likelihood is not available in closed form. This method uses simulated missing data that are independent and identically distributed and independent of the observed data. Our Monte Carlo approximation to the MLE is a consistent and asymptotically normal estimate of the minimizer theta* of the Kullback-Leibler information, as both Monte Carlo and observed data sample sizes go to infinity simultaneously. Plug-in estimates of the asymptotic variance are provided for constructing confidence regions for theta*. We give Logit-Normal generalized linear mixed model examples, calculated using an R package.
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页码:990 / 1011
页数:22
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