Diastereoselective addition of chiral azomethine ylides to cinnamoyl moieties, attached to chiral auxiliaries

被引：22
|
作者：
Karlsson, S [1 ]
Högberg, HE [1 ]
机构：
[1] Mid Sweden Univ, Dept Nat & Environm Sci, SE-85170 Sundsvall, Sweden
来源：
TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 14期
关键词：
D O I：
10.1016/S0957-4166(01)00366-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Doubly diastercoselective 1.3-dipolar cycloadditions of chiral azomethine ylides to cinnamoyl moieties, attached to chiral auxiliaries, were investigated. The resulting trans-3.4-disubstituted pyrrolidines were obtained in diastereomeric ratios of up to 78:22. The influence on this ratio by the constitution of the chiral ylide,vas found to be rather small. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码：1975 / 1976
页数：2
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