Off-label uses of rituximab in dermatology

被引：27
|
作者：
Carr, David R. [1 ]
Heffernan, Michael P. [1 ]
机构：
[1] Wright State Univ, Sch Med, Div Dermatol, Dayton, OH 45408 USA
来源：
DERMATOLOGIC THERAPY | 2007年 / 20卷 / 04期
关键词：
biologics; rituximab;
D O I：
10.1111/j.1529-8019.2007.00141.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Since its approval in 1997 by the FDA, rituximab has been approved for use in certain B-cell lymphomas and treatment-resistant rheumatoid arthritis. Over the past 10 years, many case reports have indicated rituximab's efficacy in a number of inflammatory conditions in dermatology. This article includes a review of the mechanism of action, dosing, and side effect profile, as well as a review of the current literature on off-label uses of the CD20(+) B-cell antagonist rituximab.
引用
收藏
页码：277 / 287
页数：11
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