Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

被引:16
|
作者
Oliva, E. [1 ,5 ]
Mathiron, D. [2 ,5 ]
Bertaut, E. [3 ,5 ]
Landy, D. [3 ,5 ]
Cailleu, D. [2 ,5 ]
Pilard, S. [2 ,5 ]
Clement, C. [4 ,5 ]
Courot, E. [4 ,5 ]
Bonnet, V. [1 ,5 ]
Djedaini-Pilard, F. [1 ,5 ]
机构
[1] Univ Picardie Jules Verne, LG2A UMR 7378 CNRS, Lab Glycochim Antimicrobiens & Agroresources, 33 Rue Saint Leu, F-80039 Amiens, France
[2] Univ Picardie Jules Verne, Plateforme Analyt, 33 Rue Saint Leu, F-80039 Amiens, France
[3] ULCO, UCEIV, EA 4492, F-59140 Dunkerque, France
[4] Univ Reims, UFR Sci, URVVC, EA 4707, BP 1039,Moulin Housse, F-51687 Reims, France
[5] UFR Sci Exactes & Naturelles, ESFR Condorcet Agrosci Environm & Dev Durable FR, BP 1039 Moulin Housse Batiment 18, F-51687 Reims 02, France
来源
RSC ADVANCES | 2018年 / 8卷 / 03期
关键词
RESVERATROL/HYDROXYPROPYL-BETA-CYCLODEXTRIN; GRAPEVINE CELL-CULTURES; TRANS-RESVERATROL; MASS-SPECTROMETRY; INCLUSION COMPLEX; LIQUID-CHROMATOGRAPHY; STILBENE; HPLC; WINES;
D O I
10.1039/c7ra11619e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).
引用
收藏
页码:1528 / 1538
页数:11
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