A Self-restricted CRISPR System to Reduce Off-target Effects

被引:63
|
作者
Chen, Yanhao [1 ,2 ]
Liu, Xiaojian [1 ,2 ]
Zhang, Yongxian [1 ,2 ]
Wang, Hui [2 ,3 ]
Ying, Hao [2 ,3 ]
Liu, Mingyao [4 ,5 ]
Li, Dali [4 ,5 ]
Lui, Kathy O. [6 ,7 ]
Ding, Qiurong [1 ,2 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, CAS Key Lab Nutr & Metab, Inst Nutr Sci, Shanghai, Peoples R China
[2] Univ Chinese Acad Sci, Shanghai, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Biol Sci, CAS Key Lab Food Safety Res, Inst Nutr Sci, Shanghai, Peoples R China
[4] East China Normal Univ, Shanghai Key Lab Regulatory Biol, Inst Biomed Sci, Shanghai, Peoples R China
[5] East China Normal Univ, Sch Life Sci, Shanghai, Peoples R China
[6] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Chem Pathol, Shatin, Hong Kong, Peoples R China
[7] Chinese Univ Hong Kong, Prince Wales Hosp, Li Ka Shing Inst Hlth Sci, Shatin, Hong Kong, Peoples R China
关键词
CAS9; NUCLEASES; DELIVERY;
D O I
10.1038/mt.2016.172
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:1508 / 1510
页数:3
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