Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles

被引:28
|
作者
Praburaman, Loganathan [1 ]
Jang, Jum-Suk [1 ]
Govarthanan, Muthusamy [1 ]
Arumugam, Sengottaiyan [2 ]
Manoharan, Koildhasan [3 ]
Cho, Kwang-Min [4 ]
Cho, Min [1 ]
Kamala-Kannan, Seralathan [1 ]
Oh, Byung-Taek [1 ]
机构
[1] Chonbuk Natl Univ, Adv Inst Environm & Biosci, Div Biotechnol, Coll Environm & Bioresource Sci, Iksan 570752, South Korea
[2] Mahendra Arts & Sci Coll, PG & Res Dept Biotechnol, Namakkal, Tamil Nadu, India
[3] Raja Duraisingam Govt Arts Coll, Dept Bot, Sivagangai, Tamil Nadu, India
[4] RDA, Natl Inst Crop Sci, Iksan, Jeonbuk, South Korea
基金
新加坡国家研究基金会;
关键词
cytotoxicity; hemolysis; antibacterial activity; piper betle; phytopathogens; GREEN SYNTHESIS; SILVER NANOPARTICLES; LEAF EXTRACT; BIOSYNTHESIS; ANTIOXIDANT; CHITOSAN; LEAVES;
D O I
10.3109/21691401.2015.1029630
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV-visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50-100 nm. The scanning electron microscopy (SEM)-energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 mu g/mL.
引用
收藏
页码:1400 / 1405
页数:6
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