T cell apoptosis signaling biomarker of PD-1 engagement in cancer patients

被引:0
|
作者
Zhao, Wei [1 ]
Dong, Haidong [1 ]
机构
[1] Mayo Clin, Coll Med, Rochester, MN USA
关键词
D O I
10.1158/1538-7445.AM2014-2552
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2552
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Programmed Death-1 Receptor (PD-1) as a Potential Prognosis Biomarker for Ovarian Cancer Patients
    Pawlowska, Anna
    Suszczyk, Dorota
    Tarkowski, Rafal
    Paduch, Roman
    Kotarski, Jan
    Wertel, Iwona
    CANCER MANAGEMENT AND RESEARCH, 2020, 12 : 9691 - 9709
  • [22] PD-1 and PD-L1 Up-regulation Promotes T-cell Apoptosis in Gastric Adenocarcinoma
    Chiu, Ying-Ming
    Tsai, Chung-Lin
    Kao, Jung-Ta
    Hsieh, Chin-Tung
    Shieh, Dong-Chen
    Lee, Yi-Ju
    Tsay, Gregory J.
    Cheng, Ken-Sheng
    Wu, Yi-Ying
    ANTICANCER RESEARCH, 2018, 38 (04) : 2069 - 2078
  • [23] Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer
    Roper, Nitin
    Velez, Moises J.
    Chiappori, Alberto
    Kim, Yoo Sun
    Wei, Jun S.
    Sindiri, Sivasish
    Takahashi, Nobuyuki
    Mulford, Deborah
    Kumar, Suresh
    Ylaya, Kris
    Trindade, Christopher
    Manukyan, Irena
    Brown, Anna-Leigh
    Trepel, Jane B.
    Lee, Jung-Min
    Hewitt, Stephen
    Khan, Javed
    Thomas, Anish
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [24] Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer
    Nitin Roper
    Moises J. Velez
    Alberto Chiappori
    Yoo Sun Kim
    Jun S. Wei
    Sivasish Sindiri
    Nobuyuki Takahashi
    Deborah Mulford
    Suresh Kumar
    Kris Ylaya
    Christopher Trindade
    Irena Manukyan
    Anna-Leigh Brown
    Jane B. Trepel
    Jung-Min Lee
    Stephen Hewitt
    Javed Khan
    Anish Thomas
    Nature Communications, 12
  • [25] Roles of PD-1/PD-L1 Pathway: Signaling, Cancer, and Beyond
    Ai, Luoyan
    Xu, Antao
    Xu, Jie
    REGULATION OF CANCER IMMUNE CHECKPOINTS: MOLECULAR AND CELLULAR MECHANISMS AND THERAPY, 2020, 1248 : 33 - 59
  • [26] PD-1 engagement provides an inhibitory signal which downregulates T cell alloresponses in vivo.
    Blazar, BR
    Carreno, BM
    Panoskaltsis-Mortari, A
    Carter, LJ
    Iwai, Y
    Yagita, H
    Nishimura, H
    Taylor, PA
    BLOOD, 2002, 100 (11) : 72A - 72A
  • [27] Increased PD-1 are assiciated with the suppressive immunophenotype of T cell in patients with brucellosis
    Zhang, F.
    Zhu, Y.
    Li, Z.
    Ding, J.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 426 - 427
  • [28] Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo
    Rota, Giorgia
    Niogret, Charlene
    Anh Thu Dang
    Barros, Cristina Ramon
    Fonta, Nicolas Pierre
    Alfei, Francesca
    Morgado, Leonor
    Zehn, Dietmar
    Birchmeier, Walter
    Vivier, Eric
    Guarda, Greta
    CELL REPORTS, 2018, 23 (01): : 39 - 49
  • [29] Regulation of PD-1 in T cells for cancer immunotherapy
    Yu, Xibao
    Gao, Rili
    Li, Yangqiu
    Zeng, Chengwu
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 881
  • [30] PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
    Tim Wartewig
    Zsuzsanna Kurgyis
    Selina Keppler
    Konstanze Pechloff
    Erik Hameister
    Rupert Öllinger
    Roman Maresch
    Thorsten Buch
    Katja Steiger
    Christof Winter
    Roland Rad
    Jürgen Ruland
    Nature, 2017, 552 : 121 - 125