Rational design and efficient synthesis of a fluorescent-labeled jasmonate

被引:23
|
作者
Liu, Songbai [1 ]
Wang, Wu-Hong [2 ]
Dang, Ya-Li [3 ]
Fu, Yuanqing [1 ]
Sang, Ruocheng [1 ]
机构
[1] Zhejiang Univ, Dept Food Sci & Nutr, Hangzhou 310058, Zhejiang, Peoples R China
[2] Zhejiang Acad Agr Sci, Inst Vegetable, Hangzhou 310021, Zhejiang, Peoples R China
[3] Zhejiang Acad Med Sci, Inst Hlth Food, Hangzhou 310013, Zhejiang, Peoples R China
关键词
Jasmonate; Fluorescent probe; Synthesis; Design; Biological activity; PROTEIN;
D O I
10.1016/j.tetlet.2012.06.006
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A fluorescent-labeled jasmonate was rationally designed based on examination of the model of interaction between the jasmonate and its receptor. An efficient synthetic route has been developed for this molecule. The biological activity of this fluorescent probe was retained which was similar to that of the methyl jasmonate as examined by root growth inhibition bioassay. This fluorescent probe will greatly facilitate biological studies of jasmonates through fluorescent imaging. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4235 / 4239
页数:5
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