Potential Visualization of Sorafenib-Induced Acidosis Using 11C-Acetate PET/CT in Patients With Hepatocellular Carcinoma

被引：1

作者：

Kwon, Seong Young ^{[1
]}

Kim, Dong-Yeon ^{[1
]}

Min, Jung-Joon ^{[1
]}

Bae, Woo Kyun ^{[2
]}

机构：

[1] Chonnam Natl Univ, Hwasun Hosp, Dept Nucl Med, Jeonnam, South Korea

[2] Chonnam Natl Univ, Hwasun Hosp, Dept Oncol, 322 Seoyang Ro, Hwasun 519763, Jeonnam, South Korea

来源：

CLINICAL NUCLEAR MEDICINE | 2018年 / 43卷 / 01期

关键词：

C-11-acetate PET; CT; hepatocellular carcinoma; metabolic acidosis; sorafenib; C-11-ACETATE; SCAN;

D O I：

10.1097/RLU.0000000000001879

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

C-11-acetate uptake could be increased in physiologic or inflammatory conditions without evidence of cancer. We report a hepatocellular carcinoma patient with sorafenib-induced metabolic acidosis, who showed increased hepatic uptake of C-11-acetate. C-11-acetate PET/CT might be a potentially useful surrogate marker to monitor these adverse effects via the changes in C-11-acetate uptake patterns from before to after drug withdrawal.

引用

页码：31 / 32

页数：2

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