Potential Visualization of Sorafenib-Induced Acidosis Using 11C-Acetate PET/CT in Patients With Hepatocellular Carcinoma

被引：1
|
作者：
Kwon, Seong Young [1 ]
Kim, Dong-Yeon [1 ]
Min, Jung-Joon [1 ]
Bae, Woo Kyun [2 ]
机构：
[1] Chonnam Natl Univ, Hwasun Hosp, Dept Nucl Med, Jeonnam, South Korea
[2] Chonnam Natl Univ, Hwasun Hosp, Dept Oncol, 322 Seoyang Ro, Hwasun 519763, Jeonnam, South Korea
来源：
CLINICAL NUCLEAR MEDICINE | 2018年 / 43卷 / 01期
关键词：
C-11-acetate PET; CT; hepatocellular carcinoma; metabolic acidosis; sorafenib; C-11-ACETATE; SCAN;
D O I：
10.1097/RLU.0000000000001879
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
C-11-acetate uptake could be increased in physiologic or inflammatory conditions without evidence of cancer. We report a hepatocellular carcinoma patient with sorafenib-induced metabolic acidosis, who showed increased hepatic uptake of C-11-acetate. C-11-acetate PET/CT might be a potentially useful surrogate marker to monitor these adverse effects via the changes in C-11-acetate uptake patterns from before to after drug withdrawal.
引用
收藏
页码：31 / 32
页数：2
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