Particularities of allergy in the Tropics

被引:103
|
作者
Caraballo, Luis [1 ]
Zakzuk, Josefina [1 ]
Lee, Bee Wah [2 ,3 ]
Acevedo, Nathalie [4 ]
Soh, Jian Yi [2 ,3 ]
Sanchez-Borges, Mario [5 ]
Hossny, Elham [6 ]
Garcia, Elizabeth [7 ]
Rosario, Nelson [8 ]
Ansotegui, Ignacio [9 ]
Puerta, Leonardo [1 ]
Sanchez, Jorge [10 ]
Cardona, Victoria [11 ]
机构
[1] Univ Cartagena, Immunol Res Inst, Cra 5 7-77, Cartagena, Colombia
[2] Natl Univ Hlth Syst, Khoo Teck Puat Natl Univ Childrens Med Inst, Singapore, Singapore
[3] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore 117548, Singapore
[4] Karolinska Inst, Dept Med Solna, Translat Immunol Unit, Stockholm, Sweden
[5] Ctr Med Docente La Trinidad & Clin El Avila, Allergy & Clin Immunol Dept, Caracas, Venezuela
[6] Ain Shams Univ, Childrens Hosp, Pediat Allergy & Immunol Unit, Cairo, Egypt
[7] Univ Los Andes, Fac Med, Fdn Santa Fe Bogota, Allergy Sect, Bogota, Colombia
[8] Univ Fed Parana, Rua Gen Carneiro, BR-80060000 Curitiba, Parana, Brazil
[9] Hosp Quiron Bizkaia, Dept Allergy & Immunol, Bilbao, Spain
[10] Univ Antioquia, Dept Pediat, Grad Program Allergol, Medellin, Colombia
[11] Hosp Gen Valle Hebron, Dept Internal Med, Allergy Sect, Barcelona, Spain
来源
关键词
The Tropics; Allergy; Asthma; Rhinitis; Atopic dermatitis; Helminthiases; Papular urticaria; Anaphylaxis; House dust mite; Natural history; Allergens; HOUSE-DUST-MITE; IGE CROSS-REACTIVITY; SKIN-TEST REACTIVITY; REGULATORY T-CELLS; VITAMIN-D LEVELS; ASCARIS-LUMBRICOIDES INFECTION; INCLUDING BLOMIA-TROPICALIS; PROSPECTIVE-BIRTH-COHORT; HUMAN HOOKWORM INFECTION; PRIMARY-SCHOOL CHILDREN;
D O I
10.1186/s40413-016-0110-7
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but aspects of their prevalence, natural history, risk factors, sensitizers and triggers are not well defined and some are expected to be different from those in temperate zone countries. The aim of this review is to investigate if allergic diseases in the Tropics have particularities that deserve special attention for research and clinical practice. Such information will help to form a better understanding of the pathogenesis, diagnosis and management of allergic diseases in the Tropics. As expected, we found particularities in the Tropics that merit further study because they strongly affect the natural history of common allergic diseases; most of them related to climate conditions that favor permanent exposure to mite allergens, helminth infections and stinging insects. In addition, we detected several unmet needs in important areas which should be investigated and solved by collaborative efforts led by the emergent research groups on allergy from tropical countries.
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收藏
页数:44
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